Seva is a global eye care nonprofit whose mission is to transform lives and strengthen communities by restoring sight and preventing blindness. Seva works with underserved communities in more than 20 countries across Asia, Africa, and the Americas. Their annual demonstrated impact includes:

• Reaching over 6.5 million individuals.
• Establishing 27 new vision centers serving underserved communities, providing over 3.6 million people with access to eye care.
• Screening 332,963 children for eye problems.
• Giving 59,000 kids glasses.
• Operating on 12,110 children to preserve or restore their vision.
• Training 4,719 individuals, ranging from doctors to community health promoters, in eye care.

Unlimit Health works with Ministries of Health and Education in sub-Saharan African countries to support programs controlling and eliminating two types of parasitic worm infections: schistosomiasis and soil-transmitted helminthiasis. The majority of programs treat school-aged children, but can also include at risk adults. Their annual demonstrated impact includes:

• Developing a new strategy for sustainable impact and disease elimination, including water and sanitation-focused approaches to reducing disease transmission, which complements extensive treatment programs. 
• Testing an approach to community-driven planning of environmental and behavioral action to reduce the risk of transmission of schistosomiasis.

Sanku – Project Healthy Children’s mission is to provide children everywhere with the simple, inexpensive, basic nutritional support they require to survive and thrive. Sanku – Project Healthy Children focuses on achieving wide micronutrient coverage for at risk communities in Africa and beyond. Their annual demonstrated impact includes:

• 2024 achievements include:
  
  In June 2024, Sanku launched its Nutrient Premix Blending Factory in Dar Es Salaam, Tanzania. The first of its kind in East and Central Africa. The factory is expected to provide affordable, high-quality nutrient premix locally, supporting millers in their fortification efforts and reducing logistical challenges. The new factory gives millers convenient access to high-quality nutrient premix produced based on each country’s fortification standards and includes Folic Acid, Vitamin B12, Zinc, Iron micronutrients among others. 70% of the packaging and raw materials, including the wheat carrier, essential for nutrient premix, will be sourced from local millers.
•  

One Acre Fund helps smallholder African farmers boost productivity by delivering a bundle of services directly to their doorsteps, including start-up financing, high-quality farming inputs, agricultural training, and market facilitation to help maximize profits. These tools help farmers increase their yield per acre, sales, and household income. Their annual demonstrated impact includes:

• Boosting incomes by an average of 40%, translating to $115 in new profits, by helping farmers improve their farm productivity in Burundi and Rwanda.
• Equipping farmers to achieve $316 million in new profits and assets through their full-service program and partnerships, marking over $1 billion in cumulative farmer impact generated since their founding in 2006.
• Planting 200 million cost-effective tree seedlings, with a trajectory to reach 1 billion trees by 2030. 
• Launching a full-scale program in Nigeria after five years of pilot operations, which will contribute towards improved food security and climate resilience.

Malaria Consortium delivers programs that protect the poorest and most marginalized children in Africa and Asia from a range of deadly diseases, including malaria and pneumonia. The Seasonal Malaria Chemoprevention (SMC) project is an extremely cost-effective and evidence-based approach to protect children under 5 from malaria. Their annual demonstrated impact includes:

• Delivering seasonal malaria chemoprevention to 24 million children, up from 20 million in the previous year. 
• Supporting ministries of health in Ethiopia and Chad to create national pediatric pneumonia control strategies.

The Iodine Global Network (IGN) is the leading global organization supporting the elimination of iodine deficiency, the most common cause of brain damage in newborns. IGN supports healthy iodine nutrition through a safe, effective, and affordable solution: iodized salt.

Their annual demonstrated impact includes:

• Advocating with the government to widen salt iodization in Sri Lanka, protecting Sri Lanka’s population from iodine deficiency. 
• Conducting a review of efforts to support small-scale producers in iodizing salt. In countries such as Senegal, Ghana, Tanzania, Mozambique and Cambodia, these producers supply salt to households in poor or remote areas who are not protected from iodine deficiency.

Living Goods supports and trains local community health workers, the majority of whom are women, to deliver lifesaving medicines, health education, diagnoses, and health products to millions of people who need them in Burkina Faso, Kenya, and Uganda. They focus especially on preventing and treating the leading causes of child deaths. Their annual demonstrated impact includes:

• Supporting over 12,000 community health workers with training, digital literacy, and digital tools, bringing basic healthcare to the most in need in Kenya, Uganda, and Burkina Faso with the use of advanced digital tools to transform health systems.
• Measuring a 46% reduction in child mortality in areas impacted by droughts where Living Goods-supported community healthcare workers operate, suggesting an effective healthcare workforce reduces the number of children who might have died due to drought, and that investing in improved community healthcare helps build climate resilience in low-income areas.

Helen Keller Intl’s Vitamin A Supplementation programs provide critical nutrition to children around the world at risk for vitamin A deficiency, a condition that can lead to blindness and death. Their annual demonstrated impact includes:

• Supporting 388,000 families with education and tools to grow, prepare, and sell vitamin A-rich foods. 
• Providing 32 million children under the age of 5 with two doses of vitamin A.

GiveDirectly provides unconditional cash transfers using cellphone technology to some of the world’s poorest people, as well as refugees, urban youth, and disaster victims. They also are currently running a historic Universal Basic Income initiative, delivering a basic income to 20,000+ people in Kenya in a twelve-year study. Their annual demonstrated impact includes:

• Sending cash transfers to 139,968 people in 12 countries. 
• Improving government relations to scale their Africa-based poverty relief programs, refining their ability to respond to international crises.
• Scoping expansion in India and Bangladesh.

The Fred Hollows Foundation has restored sight to more than 2.5 million people. Their work includes supporting programs to deliver more than 200 million doses of antibiotics for trachoma, working with communities to improve their own eye health through life-changing surgeries and treatments, training doctors and health workers, and pushing for change at all levels. Their annual demonstrated impact includes:

• Serving over 500,000 patients with eye operations and treatments. 
• Providing over 4 million people with antibiotics for trachoma. 
• Training over 50,000 surgeons, nurses, and teachers.

Fistula Foundation is the global leader in treating obstetric fistula, a devastating childbirth injury that leaves women incontinent and often humiliated and shunned by their communities. In addition to covering direct surgery costs, Fistula Foundation also supports surgeon training, facilities equipment, grassroots community outreach, and holistic post-surgery reintegration. Their annual demonstrated impact includes:

• Providing over 10,000 surgeries to repair childbirth injuries, including fistula.
• Supporting 8 new treatment partners throughout Africa, expanding fistula repair services into Liberia and Sierra Leone. 
• Launching a new treatment network in Tanzania.

Evidence Action scales low-cost health interventions that improve the wellbeing of hundreds of millions of people in Africa and Asia. The organization currently has four programs: Safe Water Now, Deworm the World, Equal Vitamin Access, and Syphilis-Free Start. Evidence Action’s Accelerator drives new program development, refining high-potential and cost-effective interventions.

Their demonstrated impact includes:

• Providing access to safe drinking water, which has saved more than 15,000 lives of children under 5 and averted over 3 million diarrhea cases in young children. 
• Helping governments deliver over 2 billion deworming treatments in the last decade, which is estimated to produce $23B in productivity gains.
• Reaching over 515 million people globally with interventions since their founding.

Village Enterprise equips the extreme poor in Africa with resources to start sustainable businesses through a four-part program: entrepreneurship training, a cash grant, business mentoring, and a savings group. Village Enterprise also has a sustained focus on increasing gender equity. In 2021, 83% of first-time entrepreneurs in the program were women. Their annual demonstrated impact includes:

• Launching operations in Ethiopia with the DREAMS for Refugees partnership with Mercy Corps, which aims to start 1,200 businesses within the year and 3,600 businesses long term. 
• Integrating their poverty graduation model, which provide business mentorship, seed capital, and savings and investment training, into government social protection programs in Kenya and Rwanda.

Population Services International helps women live healthier lives and plan the families they desire through a network of locally-rooted, globally-connected organizations working to achieve consumer-powered healthcare. Their annual demonstrated impact includes:

• Reaching 14.6 million consumers through accelerated market growth and systems change by working with governments.  
• Reaching 5.8 million consumers through their social business model by funding shops where individuals may access basic medicines and contraceptives.

New Incentives educates caregivers about the importance of vaccinating children and disburses cash incentives that are conditional on infants receiving four life-saving vaccines, provided through government clinics free of charge. New Incentives also works with government partners to improve vaccine supply. Their annual demonstrated impact includes:

• Enrolling over 1.5 million infants for vaccines.
• Expanding into 4 new states in northern Nigeria, Gombe, Kano, Kaduna, and Kebbi, for a total of 9 states of operation. 
• Increasing their cash incentives after gathering detailed feedback from caregivers and stakeholders.

Development Media International runs large-scale media campaigns in low-income countries to create informative and engaging programming that focuses on maternal and child health, nutrition, hygiene and sanitation, sexual reproductive health, and early childhood development. Their annual demonstrated impact includes:

• Reaching over 90 million people with media campaigns on health subjects in sub-Saharan Africa. 
• Launching projects in Tanzania, Madagascar, Burkina Faso and Mozambique that have been shown to increase life-saving treatment for severe childhood illnesses. 
• Saving an estimated 8,500 children’s lives with a media campaign in Mozambique that helps parents and caregivers understand when and how to seek healthcare services for their ill children.
• Launching two pilot projects that aim to improve health outcomes in young adults in Zambia.

​Educate Girls aims to provide equitable access to education for all girls in India. Its primary beneficiaries are out-of-school girls in rural communities. They strive to boost school enrollment and learning with local volunteers who mobilize parents and communities and by delivering supplementary remedial learning curriculum. Their annual demonstrated impact includes:

• Re-enrolling 250,000 out-of-school girls back in education.
• Supporting nearly 300,000 children with their remedial education.
• Signing of an agreement with the State Government of Rajasthan to train over 20,000 government teachers and educational officials in the identification and enrollment of out-of-school children across all 33 districts of the state.

Teaching at the Right Level Africa aims to ensure that in over 12 countries and counting across Africa, every child is being taught effectively. Rather than strictly focusing on age-based curriculum requirements, a practice that leaves students behind without opportunities to catch up, their approach involves teaching students at their actual learning levels. Their annual demonstrated impact includes:

• Improving learning outcomes for 5 million children in sub-Saharan Africa by way of governments institutionalizing the Teaching at the Right Level approach in Côte d’Ivoire, Nigeria and Zambia, reaching over 1,000 schools in Côte d’Ivoire, over 2,000 schools in Nigeria across 7 states, and over 5,000 schools in Zambia, more than half the primary schools in the country.
• Aiding children in increased their reading and arithmetic results by 14 to 37 percentage points.

Breakthrough Trust works on culture-based change in India, focusing their programs on girls and boys aged 11 to 24. They partner with the government and help redesign school curricula to include material on gendered violence, as well as running mass media campaigns to reach a large audience. Their annual demonstrated impact includes:

• Transforming gender norms by working in 13 districts and 4 states within India, including Haryana, Uttar Pradesh, Jharkhand, and Delhi/NCR. 
• Collaborating with state governments in Punjab and Odisha and education departments to embed a gender lens into the middle school curricula and train teachers and school leaders to build gender sensitivity.

CEDOVIP is a locally-run, Uganda-based nonprofit that establishes and helps run community-led programs focused on reducing violence throughout Kampala and northern Uganda, with ambitious plans to scale their work throughout the rest of the country. Their annual demonstrated impact includes:

• Coordinating a Learning Center to provide more than 300 activists and practitioners with practical skills to effectively mobilize communities for violence prevention in collaboration with Raising Voices. 
• Developing a handbook with protocols for the Ugandan police force to prevent and respond to violence against women and girls.
• Influencing parliamentary approval of the Domestic Violence Bill in Uganda.

Against Malaria Foundation works to prevent the spread of malaria by distributing long-lasting, insecticide-treated mosquito nets to susceptible populations in poor countries. Their annual demonstrated impact includes:

• Distributing 36.5 million mosquito nets over 12 months, protecting 66 million people. The impact of these nets is estimated to be 24,300 deaths averted, 12 to 24 million malaria cases prevented, and US$880 million in improved economic performance.